glossary

Absolute risk reduction/increase

The absolute arithmetic difference in rates of bad outcomes between experimental and control participants in a trial, calculated as the experimental event rate (EER) and the control event rate (CER), and accompanied by a 95% CI. Depending on circumstances it can be reduction in risk (death or cardiovascular outcomes, for instance, in trials of statins), or an increase (pain relied, for instance, in trials of analgesics).

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